The maps below were used to determine how UVB exposure and vitamin D affect risk of cancer incidence and death as described in the Word document Ultraviolet B Exposure, Vitamin D, and the Risk of Cancer.
UVB Exposure, Vitamin D, and the Risk of Cancer
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|UV Exposure by Geography||Breast Cancer Mortality Rates by Geography||Colon Cancer Mortality by Geography||Ovarian Cancer Mortality by Geography|
Anticancer Res. 2018 Feb;38(2):1121-1136.
The vitamin D-cancer prevention hypothesis has been evaluated through several types of studies, including geographical ecological studies related to indices of solar ultraviolet-B (UVB) dose (the primary source of vitamin D for most people), observational studies related to UVB exposure or serum 25-hydroxyvitamin D [25(OH)D] concentrations, laboratory studies of mechanisms, and clinical trials. Each approach has strengths and limitations. Ecological studies indirectly measure vitamin D production and incorporate the assumption that vitamin D mediates the effect of UVB exposure. Findings from observational studies with long follow-up times are affected by changing 25(OH)D concentrations over time. Most clinical trials have been poorly designed and conducted, based largely on guidelines for pharmaceutical drugs rather than on nutrients. However, three clinical trials do support the hypothesis. In general, the totality of the evidence, as evaluated using Hill's criteria for causality in a biological system, supports the vitamin D-cancer prevention hypothesis.
The primary objective of SUNARC is to do research on and provide information on the prevention of chronic disease through lifestyle and dietary choices.
To this end, SUNARC will conduct research and provide information on (or advance the understanding and acceptance of) ultraviolet radiation, solar and artificial, as an important positive health factor, not only for musculoskeletal diseases, but also for chronic diseases such as autoimmune diseases, cancer, heart disease, multiple sclerosis, and neurological disorders.
The approach will be to have the most comprehensive summary of data, research findings, health policies, and links to information regarding the health benefits of ultraviolet radiation and vitamin D. In addition, SUNARC will conduct research and provide information about the role of nutrition as risk and risk reduction factors for chronic diseases such as Alzheimer's disease, autoimmune diseases, cancer, heart disease, musculoskeletal diseases, and rheumatoid arthritis.
William Grant has 142 publications on vitamin D listed at pubmed.gov as of December 31, 2011, and an additional 17 publications on ultraviolet radiation. To access many of them, go to www.pubmed.gov and enter “Grant W, vitamin D” in the search field. 47 have open access/free download; 21 are reviews. Another 5 papers on ultraviolet have open access. He publishes about 30 articles and letters to the editor each year, so check back often for important updates on ultraviolet B and vitamin D.
The health benefits of ultraviolet-B (UVB) irradiance and vitamin D are coming into sharper focus as more research results are published. There are now about 100 conditions and diseases linked to low serum 25-hydroxyvitamin D concentrations.
Documents on about 75 of these diseases and conditions are posted at www.vitamindcouncil.org/health-conditions
Sunlight, Nutrition and Health Research Center is a California non-profit charitable organization.
California Corporate number 264698; Federal Employer I.D. number 20-1115065.